Tang W, Young E, Detrano R, Doherty T, French W, Brundage B
Saint John's Cardiovascular Research Center, Department of Medicine, Harbor-UCLA Medical Center, Torrance 90509.
Invest Radiol. 1994 Feb;29(2):147-9. doi: 10.1097/00004424-199402000-00004.
Digital subtraction fluoroscopy, an inexpensive screening test for coronary atherosclerosis, is highly sensitive in detecting coronary calcifications. However, no previous study has reported interobserver agreement for this test.
Six hundred and thirty-one subjects underwent digital subtraction fluoroscopy in the 60 degrees left anterior oblique projection. Images were acquired with pulsed fluoroscopy at 15 frames per second. An averaged mask was subtracted from successive images. These fluoroscopic images were stored on a digital disk and replayed in cine loop format. An observer, blinded to clinical information, read the fluoroscopic studies for the presence of calcium in the left main-left anterior descending artery, circumflex artery, and right coronary artery. The images were then stored on digital tape and reread by a second blinded observer.
The percentages of interobserver agreement regarding the presence and absence of calcium in left main-left anterior descending, circumflex, and right coronary arteries, were 91.9%, 92.9%, and 92.2%, respectively. The overall kappa values, which are 0.85, 0.77, and 0.82 in left main-left anterior descending, circumflex, and right coronary arteries, respectively, show a highly significant level of agreement (P < .0001).
Digital subtraction fluoroscopy is a reliable screening test for coronary calcifications.
数字减影荧光透视是一种用于筛查冠状动脉粥样硬化的低成本检测方法,在检测冠状动脉钙化方面具有高度敏感性。然而,此前尚无研究报道该检测方法的观察者间一致性。
631名受试者接受了左前斜60度投影的数字减影荧光透视检查。采用脉冲荧光透视以每秒15帧的速度采集图像。从连续图像中减去平均蒙片。这些荧光透视图像存储在数字磁盘上,并以电影循环格式回放。一名对临床信息不知情的观察者阅读荧光透视研究,以检查左主干-左前降支、回旋支和右冠状动脉中是否存在钙化。然后将图像存储在数字磁带上,由另一名不知情的观察者重新阅读。
左主干-左前降支、回旋支和右冠状动脉中钙存在与否的观察者间一致率分别为91.9%、92.9%和92.2%。左主干-左前降支、回旋支和右冠状动脉的总体kappa值分别为0.85、0.77和0.82,显示出高度显著的一致性水平(P < .0001)。
数字减影荧光透视是一种可靠的冠状动脉钙化筛查检测方法。