Tassler P L, Dellon A L, Canoun C
Johns Hopkins University School of Medicine, Baltimore, Maryland.
J Hand Surg Br. 1994 Feb;19(1):48-54. doi: 10.1016/0266-7681(94)90049-3.
Traditional histological staining techniques, as well as elastin-specific antibodies and electron microscopy, have been used to assess the distribution of elastin within the peripheral nerve. The location of the elastin identified by the VerHoeff-VanGiesen or Weigert stains has been shown to coincide with the unambiguous identification of elastin by immunospecific stains and electron microscopy. Elastin is located in all three connective layers of the peripheral nerve. Thick elastic fibres, consisting of amorphous elastin protein and microfibrils, are located consistently in the perineurium and, to a lesser extent, in the epineurium. The endoneurium contains small collections of elastic fibres widely distributed between the axons. Compared with collagen, the overall content of elastin, however, is small, suggesting that the visco-elastic properties of peripheral nerve may be due primarily to collagen.
传统的组织学染色技术，以及弹性蛋白特异性抗体和电子显微镜，已被用于评估弹性蛋白在周围神经中的分布。经VerHoeff-VanGiesen或Weigert染色鉴定出的弹性蛋白位置，已被证明与通过免疫特异性染色和电子显微镜对弹性蛋白的明确鉴定结果一致。弹性蛋白存在于周围神经的所有三层结缔组织中。由无定形弹性蛋白和微原纤维组成的粗大弹性纤维始终存在于神经束膜中，在神经外膜中的含量较少。神经内膜含有少量弹性纤维，广泛分布于轴突之间。然而，与胶原蛋白相比，弹性蛋白的总体含量较少，这表明周围神经的粘弹性特性可能主要归因于胶原蛋白。
