Popławski A, Kaliszewicz Z, Cieślak M, Popławska T
Kliniki Nefrologii AM, Białymstoku.
Pol Tyg Lek. 1993;48(20-22):452-4.
The study aimed at comparing various techniques enabling relatively rapid assay of intermediate molecular weight compounds in blood. A content of intermediate molecular weight compounds concentrations in blood ultrafiltrate obtained with routinely performed hemodialysis, in dialysate fluid after clearance of blood serum, in supernatant of deproteinized blood serum, and dialysate after clearance of deproteinized serum supernatant were compared. No correlation between the content of intermediate molecular weight compounds in dialysate after clearance of blood serum and deproteinized serum supernatant was noted. Further studies, including separation of these compounds with HPLC did not show similarities in the course of particular curves at 254 nm.
该研究旨在比较各种能够相对快速检测血液中中等分子量化合物的技术。比较了常规进行血液透析所获得的血液超滤液、血清清除后的透析液、脱蛋白血清上清液以及脱蛋白血清上清液清除后的透析液中中等分子量化合物的浓度。未发现血清清除后的透析液和脱蛋白血清上清液中中等分子量化合物的含量之间存在相关性。包括用高效液相色谱法分离这些化合物在内的进一步研究，未显示在254纳米处特定曲线的过程中有相似之处。
