库欣病垂体手术后的良性颅内高压
Benign intracranial hypertension after pituitary surgery for Cushing's disease.
作者信息
Parfitt V J, Dearlove J C, Savage D, Griffith H B, Hartog M
机构信息
University Department of Medicine, Southmead Hospital, Bristol, UK.
出版信息
Postgrad Med J. 1994 Feb;70(820):115-7. doi: 10.1136/pgmj.70.820.115.
An 11 year old girl underwent successful transsphenoidal pituitary adenomectomy for pituitary-dependent Cushing's syndrome. Three months after operation, just after stopping glucocorticoid replacement therapy, she developed benign intracranial hypertension. This resolved when exogenous glucocorticoids were restarted but occurred again when they were later stopped. On restarting glucocorticoids again, this second episode of intracranial hypertension resolved. This complication may have been due to the large fall in endogenous cortisol production after removal of her adenoma and subsequent persistent mild endogenous hypocortisolism.
一名11岁女孩因垂体依赖性库欣综合征接受了成功的经蝶窦垂体腺瘤切除术。术后三个月，在停止糖皮质激素替代治疗后不久，她出现了良性颅内高压。重新开始使用外源性糖皮质激素后，这种情况得到缓解，但后来再次停药时又再次出现。再次重新开始使用糖皮质激素后，这第二次颅内高压发作得到缓解。这种并发症可能是由于切除腺瘤后内源性皮质醇分泌大幅下降以及随后持续存在的轻度内源性皮质醇不足所致。
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