Martin N A, Linfoot J, Wilson C B
Neurosurgery. 1981 Jun;8(6):699-702. doi: 10.1227/00006123-198106000-00011.
A patient with Cushing's disease developed intracranial hypertension 1 month after the removal of an adrenocorticotropic hormone-secreting pituitary adenoma. A computed tomographic scan demonstrated normal ventricles and no intracranial mass, establishing the diagnosis of pseudotumor cerebri. The elevated intracranial pressure was apparently consequent to an abrupt reduction in circulating corticosteroids. The development of pseudotumor cerebri after the correction of endogenous hypercortisolism has not been reported previously. This potential complication of the surgical treatment of Cushing's disease can be managed with prompt recognition and appropriate treatment of the syndrome.
一名库欣病患者在切除分泌促肾上腺皮质激素的垂体腺瘤1个月后出现颅内高压。计算机断层扫描显示脑室正常且无颅内肿块,从而确诊为假性脑瘤。颅内压升高显然是由于循环皮质类固醇激素突然减少所致。内源性皮质醇增多症纠正后发生假性脑瘤此前尚未见报道。库欣病手术治疗的这一潜在并发症可通过对该综合征的及时识别和适当治疗来处理。