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[胸膜外胸廓成形术对晚期纤维空洞型肺结核患者肺力学特性及通气指标的影响]

[The effect of extrapleural thoracoplasty on the mechanical properties of lungs and ventilation indices in advanced fibrous-cavernous tuberculosis].

作者信息

Strelis A K, Lenskaia L G

出版信息

Probl Tuberk. 1994(1):23-5.

PMID:8170905
Abstract

Basing on clinical data obtained on 42 patients, the authors prove the existence of changes in all the respiratory biomechanical parameters, primarily viscosity, in response to development of advanced fibrous-cavernous tuberculosis in the lungs. Disorders in the bronchopulmonary mechanics depend on the terms of collapsosurgical intervention and its efficacy. The viscosity-induced resistance to respiration results basically from inflammation of the tracheobronchial tree and bronchospasm. An increase in the bronchial resistance in the early postoperative period occurs both in effective and uneffective extrapleural thoracoplasty, while later on it is observed only after uneffective and corrective collapsosurgical interventions. Basic biomechanical parameters of respiration (total performance, extensibility, bronchial resistance) together with spirographic and clinicoroentgenological evidence can be of help in predicting the effect of the surgery itself. A positive response of collapsosurgical interventions on respiratory biomechanics can be judged from a persistent fall in total respiratory performance irrespective of surgical effectivity.

摘要

基于42例患者的临床资料,作者证实了肺部晚期纤维空洞型肺结核发展时,所有呼吸生物力学参数(主要是黏性)均存在变化。支气管肺力学紊乱取决于胸廓成形手术的条件及其疗效。黏性引起的呼吸阻力主要源于气管支气管树的炎症和支气管痉挛。术后早期,无论是有效的还是无效的胸膜外胸廓成形术都会导致支气管阻力增加,而后期仅在无效的和矫正性胸廓成形手术后才会出现。呼吸的基本生物力学参数(总效能、可扩展性、支气管阻力)以及肺功能描记图和临床X线证据有助于预测手术本身的效果。无论手术效果如何,胸廓成形手术对呼吸生物力学的积极反应可通过总呼吸效能持续下降来判断。

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