Weise H J, Farago M
MMW Munch Med Wochenschr. 1976 Apr 2;118(14):435-8.
Rare cases of recto-sigmoid villous adenoma may show profuse mucous discharge per anum as a cardinal symptom which consequently leads to considerable losses of water and electrolytes with imminent exsiccosis uremia. In spite of these typical clinical symptoms, this disease, which occurs mainly in older people, is frequently misdiagnosed and usually only recognized late. Because of the increased danger of malignant degeneration, the poor control of this leakage of electrolytes by conservative therapy and the tendency to local relapse of this tumor, there is an absolute indication for radical surgical treatment.