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[去甲肾上腺素、乙酰胆碱及其阻滞剂对目标导向行为中皮层神经元活动的影响]

[The effect of noradrenaline, acetylcholine and their blockers on cortical neuronal activity in goal-directed behavior].

作者信息

Andrianov V V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1994 Jan-Feb;44(1):33-9.

PMID:8171902
Abstract

Neurochemical cellular mechanisms of central organization of the consecutive stages of formation of a goal-directed behavioural act were studied in cats by means of microiontophoretic application of biologically active substances. Chemical characteristics of single cortical neurons varied at different stages of behavioural act. Dynamics of spike activity at these stages changed in opposite directions during application of neurotransmitters and their antagonists. The differences were more expressed during propranolol and atropine than during noradrenaline and acetylcholine application.

摘要

通过生物活性物质的微量离子电泳应用,在猫身上研究了目标导向行为动作形成连续阶段的中枢组织的神经化学细胞机制。在行为动作的不同阶段,单个皮质神经元的化学特性有所不同。在应用神经递质及其拮抗剂期间,这些阶段的峰电位活动动态向相反方向变化。与应用去甲肾上腺素和乙酰胆碱相比,在应用普萘洛尔和阿托品期间差异更为明显。

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