犬中性粒细胞对N-甲酰甲硫氨酰-亮氨酰-苯丙氨酸和细胞松弛素B组合的反应中超氧化物生成不足。
Inadequate superoxide production by canine neutrophils in response to the combination of N-formyl-methionyl-leucyl-phenylalanine and cytochalasin B.
作者信息
Ing T S, Yu A W, Patel M, Gupta V, Khan M A, Agrawal A, Patel P
机构信息
Department of Medicine, Veterans Affairs Hospital, Hines, IL.
出版信息
Am J Vet Res. 1994 Feb;55(2):288-90.
PMID:8172421
Abstract
The formylated peptide, N-formyl-methionyl-leucyl-phenylalanine, at concentration of 0.22 microM, failed to stimulate canine neutrophils to produce adequate amounts of superoxide. Furthermore, addition of cytochalasin B did not augment superoxide generation appreciably.
摘要
浓度为0.22微摩尔的甲酰化肽N-甲酰甲硫氨酰-亮氨酰-苯丙氨酸未能刺激犬中性粒细胞产生足够量的超氧化物。此外，加入细胞松弛素B也未显著增加超氧化物的生成。
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