Chousterman M, Gretillat F, Petite J P, Acar J F, Debain P, Housset E
Nouv Presse Med. 1976 Feb 28;5(9):573-4.
This paper describes a case of disseminated gonococcal infection, a rare disease in France. A 41 year-old woman was hospitalised with acute polyarthritis and characteristics skin lesions. Jaundice and liver function abnormalities are difficult to interpret due to a preexisting alcoholic cirrhosis. The possibility of an endocarditis is raised because of a systolic murmur heard at the base of the heart. Bacteriological identification of N. Gonorrhoeae is carried out in blood culture; it has also been recovered by scrapings of a cutaneous bullae by staining only. Therapy was instituted by daily intravenous penicillin G sodium 50 000 000 u. and intramuscular gentamicin 160 mg for 45 days. There resulted good clinical and bacteriological response. The elements of clinical and bacteriological diagnosis, as well as the therapy are discussed.
本文描述了一例播散性淋球菌感染病例,这在法国是一种罕见疾病。一名41岁女性因急性多关节炎和特征性皮肤病变入院。由于既往存在酒精性肝硬化,黄疸和肝功能异常难以解释。因在心底部听到收缩期杂音,怀疑存在心内膜炎。在血培养中进行了淋病奈瑟菌的细菌学鉴定;通过仅对皮肤大疱进行刮片染色也发现了该菌。治疗方案为每日静脉注射5000万单位青霉素G钠和肌肉注射160毫克庆大霉素,持续45天。临床和细菌学反应良好。文中讨论了临床和细菌学诊断要点以及治疗方法。