一名患有假性醛固酮减少症并伴有胆结石的婴儿。

An infant with pseudohypoaldosteronism accompanied by cholelithiasis.

作者信息

Hanaki K, Ohzeki T, Iitsuka T, Nagata I, Urashima H, Tsukuda T, Nagaishi J, Shiraki K, Shimizu N, Kaibara N

机构信息

Department of Pediatrics, Faculty of Medicine, Tottori University, Yonago, Japan.

出版信息

Biol Neonate. 1994;65(2):85-8. doi: 10.1159/000244031.

DOI:10.1159/000244031

PMID:8173013

Abstract

A case of an infant with very rare concurrence of pseudohypoaldosteronism and cholelithiasis is described. Aldosterone concentration was extremely high (64.6 nmol/l; normal 0.03-4.4 nmol/l) and fludrocortisone did not have favorable effects on hyperkalemia (7.4 mEq/l) and hyponatremia (124 mEq/l). A gallstone was found using ultrasonography at age 6 months, and it was extirpated surgically. The combination has not been reported previously. The study supports the previous hypothesis that cholelithiasis is found more often in infants with dehydration or electrolyte derangement.

摘要

本文描述了一例患有极为罕见的假性醛固酮减少症与胆结石并发的婴儿病例。醛固酮浓度极高（64.6 nmol/l；正常范围为0.03 - 4.4 nmol/l），而氟氢可的松对高钾血症（7.4 mEq/l）和低钠血症（124 mEq/l）并无良好疗效。该婴儿在6个月大时通过超声检查发现胆结石，并接受了手术摘除。此前尚未有这种病症组合的报道。该研究支持了先前的假说，即脱水或电解质紊乱的婴儿更常发生胆结石。