Cigudosa J C, Calasanz M J, Pérez C, Rifón J, Cuesta B, Gullon A
Department of Genetics, University of Navarra, Pamploma, Spain.
Cancer Genet Cytogenet. 1994 Apr;73(2):169-70. doi: 10.1016/0165-4608(94)90204-6.
We describe a case of Waldenström's macroglobulinemia with a complex karyotype including a 14q+ marker. Secondary changes affected chromosomes 2, 4, 6, 7, 8, and 17. The cytogenetic significance of the changes and their prognostic value, as compared with those described in previous reports, are discussed.
我们描述了一例伴有复杂核型(包括一个14q+标记)的华氏巨球蛋白血症病例。继发性改变累及2号、4号、6号、7号、8号和17号染色体。本文讨论了这些改变的细胞遗传学意义及其与既往报道相比的预后价值。