Wang S L
Beijing Hospital for stomatology, Capital Institute of medicine.
Zhonghua Kou Qiang Yi Xue Za Zhi. 1993 Jul;28(4):228-30, 255.
This study presents a study on 23 patients with chronic obstructive parotitis (COP) in whom the sialographic changes are related to the clinical and histopathological features. The sialographic changes are divided into 4 types. The stimulated parotid flow rate (SPFR) is normal in sialography Type I patients, while SPFR is significantly reduced in Type II, III, and IV patients, as compared with healthy persons. The changes under light microscope consist of irregular dilatation and chronic inflammation of main and branching ducts with saliva deposits in the enlarged luminal system. Ultrastructural changes include degeneration of ductal epithelial cells, marked proliferation of periductal fibrous tissue, and moderate electron-dense deposits in the lumen of the dilated peripheral ducts. The extent of the histopathologic changes largely parallel the severity of the sialographic changes. These findings indicate that COP is a common inflammatory disease and that the sialographic classification reflects the severity of the disease.
本研究对23例慢性阻塞性腮腺炎(COP)患者进行了研究,这些患者的涎腺造影改变与临床及组织病理学特征相关。涎腺造影改变分为4种类型。涎腺造影I型患者的刺激腮腺流率(SPFR)正常,而与健康人相比,II型、III型和IV型患者的SPFR显著降低。光镜下改变包括主导管和分支导管不规则扩张及慢性炎症,管腔系统扩大处有唾液沉积。超微结构改变包括导管上皮细胞变性、导管周围纤维组织明显增生以及扩张的外周导管管腔内有中等电子密度沉积物。组织病理学改变的程度在很大程度上与涎腺造影改变的严重程度平行。这些发现表明COP是一种常见的炎症性疾病,涎腺造影分类反映了疾病的严重程度。