Ding K J
Department of Urology, Shandong Provincial Hospital.
Zhonghua Zhong Liu Za Zhi. 1993 Jul;15(4):311-3.
A comparative retrospective study with follow-up survey was performed on 75 male bladder cancer patients, in order to investigate the relation between bladder carcinoma and bladder-neck obstruction, and effect of combined surgical treatment for both lesion on the recurrence of bladder cancer. All the bladder cancers were confirmed by cystoscopy and histopathological examination. The pathological findings included: 69 cases of transitional cell carcinoma, 5 cases of squamous cell carcinoma and 1 case of adenocarcinoma. All patients were treated by partial cystectomy and followed-up by cystoscopy and urine exfoliative cytologic examination. Thirty patients (group I) who had bladder cancer and bladder-neck obstruction received simultaneous partial cystectomy and cystauchenotomy were compared to 21 patients (group II) who had both lesions but received partial cystectomy only, and to 24 patients (group III) who had bladder cancer only and underwent partial cystectomy. Evaluation of recurrence of bladder cancer in each group showed that recurrence occurred in 6 patients (20%) in group I, 10 patients (47.1%) in group II, and 4 patients (16.6%) in group III. The data showed that partial cystectomy combined with cystauchenotomy in patients with bladder cancer accompanied by bladder-neck obstruction significantly decreased the postoperative recurrence of tumor in comparison with the group treated by partial cystectomy alone. It is suggested that the presence of bladder-neck obstruction may exert some effects on the genesis and postoperative recurrence of bladder cancer.
对75例男性膀胱癌患者进行了一项带有随访调查的比较性回顾性研究,以探讨膀胱癌与膀胱颈梗阻之间的关系,以及对两种病变进行联合手术治疗对膀胱癌复发的影响。所有膀胱癌均经膀胱镜检查和组织病理学检查确诊。病理结果包括:69例移行细胞癌、5例鳞状细胞癌和1例腺癌。所有患者均接受了膀胱部分切除术,并通过膀胱镜检查和尿液脱落细胞学检查进行随访。将30例患有膀胱癌和膀胱颈梗阻且同时接受膀胱部分切除术和膀胱颈切开术的患者(第一组)与21例患有两种病变但仅接受膀胱部分切除术的患者(第二组)以及24例仅患有膀胱癌并接受膀胱部分切除术的患者(第三组)进行比较。对每组膀胱癌复发情况的评估显示,第一组有6例患者(20%)复发,第二组有10例患者(47.1%)复发,第三组有4例患者(16.6%)复发。数据表明,与仅接受膀胱部分切除术治疗的组相比,对伴有膀胱颈梗阻的膀胱癌患者进行膀胱部分切除术联合膀胱颈切开术可显著降低术后肿瘤复发率。提示膀胱颈梗阻的存在可能对膀胱癌的发生和术后复发产生一定影响。