Liu F S
Cancer Institute, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1993 Sep;15(5):381-4.
Two hundred and thirty-three cases of thyroid carcinoma have been analysed by pathology. All cases were followed up more than 5 years after operation. A systematic investigation on the size of tumors, histological types, tumor cell differentiation, tumor cell infiltration, metastasis in lymph nodes and the interstitial reaction was carried out. The results showed that the survival rate of patients was closely related to the size of tumor. In regard to the histological types, the papillary carcinoma was more favourable in prognosis, and the 5, 10 and 15 year survival rates were much better than those of follicular carcinoma. In the medullary carcinoma and anaplastic carcinoma, there was no patient surviving over 10 years. According to the cell differentiation, the papillary and follicular carcinomas were divided into three grades: grade I (well differentiation), grade II (moderate differentiation) and grade III (poor differentiation). In the papillary carcinoma, the survival of the patients seems to be related to the cell differentiation but without statistical significance. However, in follicular carcinoma of the thyroid, the 5, 10 and 15 year survival rates were closely related to the differentiation of cancer cells. Other factors did not show significance in the prognosis, probably because of a too small number of cases in this group.
对233例甲状腺癌进行了病理分析。所有病例均在术后随访5年以上。对肿瘤大小、组织学类型、肿瘤细胞分化、肿瘤细胞浸润、淋巴结转移及间质反应进行了系统研究。结果显示，患者的生存率与肿瘤大小密切相关。就组织学类型而言，乳头状癌预后较好，5年、10年和15年生存率均明显优于滤泡状癌。在髓样癌和未分化癌中，无患者存活超过10年。根据细胞分化程度，将乳头状癌和滤泡状癌分为三级：I级（高分化）、II级（中分化）和III级（低分化）。在乳头状癌中，患者的生存率似乎与细胞分化有关，但无统计学意义。然而，在甲状腺滤泡状癌中，5年、10年和15年生存率与癌细胞分化密切相关。其他因素在预后中未显示出显著性，可能是因为该组病例数过少。
