Moulin T, Crépin-Leblond T, Chopard J L, Bogousslavsky J
Service de Neurologie, Centre Hospitalier Régional, Besançon, France.
Eur Neurol. 1994;34(2):64-77. doi: 10.1159/000117012.
A review of hemorrhagic transformation after brain ischemia is presented. The pathological, clinical and radiological aspects are discussed with respect to recent studies. The different pathophysiological mechanisms (reperfusion, vascular rupture, size of infarction, timing of constitution) are reviewed. The role of the utilization of antithrombotic (anticoagulant and thrombolytic) agents in the production of hemorrhagic infarct is presented, and we propose a new classification of hemorrhagic infarct, based on the CT scan patterns.
本文对脑缺血后出血性转化进行了综述。结合近期研究讨论了其病理、临床和放射学方面。回顾了不同的病理生理机制(再灌注、血管破裂、梗死大小、形成时间)。阐述了抗血栓形成药物(抗凝剂和溶栓剂)在出血性梗死发生中的作用,并基于CT扫描模式提出了出血性梗死的新分类。