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多普勒超声能否改善急性溃疡出血的预后?

Does Doppler ultrasound improve the prognosis of acute ulcer bleeding?

作者信息

Kohler B, Rieman J F

机构信息

Department of Medicine, Medical Center of the Municipality of Ludwigshafen, Germany.

出版信息

Hepatogastroenterology. 1994 Feb;41(1):51-3.

PMID:8175116
Abstract

The visible vessel in the floor of the ulcer seen on endoscopy is one of the most important prognostic factors of ulcer bleeding. With the ultimate aim of improving the purely visual interpretation of the base of the ulcer, we investigated the utility of an innovative pulsed endoscopic Doppler procedure in 140 patients with acute ulcer bleeding. Agreement between the endoscopic appearance and the Doppler ultrasonographic findings was observed in only 59% of the ulcers. In all Doppler-positive ulcers, injection therapy was performed irrespective of the endoscopic appearance of the ulcer. This was repeated if the ulcer was still Doppler-positive on repeat examination. With this strategy, only 9% recurrent hemorrhages were seen, and there was no hemorrhage-associated mortality. Among the Doppler-negative lesions, which received only medical treatment, no rebleeding was observed. On the basis of these results, it would appear that a Doppler ultrasound oriented classification of ulcer bleeding is superior to the Forrest classification based on a purely visual interpretation. The endoscopic Doppler verifies the visual impression of the ulcer, identifies the indication for operative endoscopy, and can monitor the effectiveness of the latter.

摘要

内镜检查时在溃疡底部可见的血管是溃疡出血最重要的预后因素之一。为了最终改善对溃疡底部的单纯视觉判断,我们对140例急性溃疡出血患者进行了一项创新性脉冲内镜多普勒检查的效用研究。仅59%的溃疡在内镜表现与多普勒超声检查结果之间观察到一致性。在所有多普勒检查呈阳性的溃疡中,无论溃疡的内镜表现如何,均进行注射治疗。如果复查时溃疡仍为多普勒阳性,则重复治疗。采用该策略,仅观察到9%的复发性出血,且无出血相关死亡。在仅接受药物治疗的多普勒检查呈阴性的病变中,未观察到再出血。基于这些结果,似乎基于多普勒超声的溃疡出血分类优于基于单纯视觉判断的福里斯特分类。内镜多普勒可验证对溃疡的视觉印象,确定手术内镜检查的适应证,并可监测其有效性。

相似文献

1
Does Doppler ultrasound improve the prognosis of acute ulcer bleeding?多普勒超声能否改善急性溃疡出血的预后?
Hepatogastroenterology. 1994 Feb;41(1):51-3.
2
Endoscopic injection therapy of Forrest II and III gastroduodenal ulcers guided by endoscopic Doppler ultrasound.内镜多普勒超声引导下对福雷斯特II级和III级胃十二指肠溃疡进行内镜注射治疗。
Endoscopy. 1993 Mar;25(3):219-23. doi: 10.1055/s-2007-1010296.
3
Endoscopic Doppler ultrasound after injection therapy for peptic ulcer hemorrhage.内镜下注射治疗消化性溃疡出血后的多普勒超声检查
Hepatogastroenterology. 2004 Jul-Aug;51(58):1206-9.
4
The endoscopic Doppler: its value in evaluating gastroduodenal ulcers after hemorrhage and as an instrument of control of endoscopic injection therapy.
Scand J Gastroenterol. 1991 May;26(5):471-6. doi: 10.3109/00365529108998568.
5
[Endoscopic Doppler ultrasound in gastroduodenal ulcer hemorrhage].[内镜多普勒超声在胃十二指肠溃疡出血中的应用]
Fortschr Med. 1992 Jun 30;110(18):336-9.
6
Role of Doppler US in acute peptic ulcer hemorrhage: can it predict failure of endoscopic therapy?多普勒超声在急性消化性溃疡出血中的作用:它能否预测内镜治疗的失败?
Gastrointest Endosc. 2000 Sep;52(3):315-21. doi: 10.1067/mge.2000.106688.
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Acute ulcer bleeding. A prospective randomized trial to compare Doppler and Forrest classifications in endoscopic diagnosis and therapy.
Dig Dis Sci. 1997 Jul;42(7):1370-4. doi: 10.1023/a:1018877602113.
8
[Significance of the ulcer vessel in acute ulcer hemorrhage--value of local endoscopic therapy in combination with endoscopic Doppler ultrasound].
Z Gastroenterol. 1992 Jul;30(7):481-5.
9
Effect of programmed endoscopic follow-up examinations on the rebleeding rate of gastric or duodenal peptic ulcers treated by injection therapy: a prospective, randomized controlled trial.内镜定期随访检查对注射疗法治疗的胃或十二指肠消化性溃疡再出血率的影响:一项前瞻性随机对照试验。
Endoscopy. 1998 Sep;30(7):583-9. doi: 10.1055/s-2007-1001360.
10
Prediction of rebleeding in peptic ulcers by visual stigmata and endoscopic Doppler ultrasound criteria.通过可视溃疡特征和内镜多普勒超声标准预测消化性溃疡再出血
Endoscopy. 1990 Mar;22(2):68-71. doi: 10.1055/s-2007-1012795.

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Endoscopic Doppler probe ultrasonography for detecting blood flow at post-endoscopic submucosal dissection ulcers of the stomach.内镜多普勒探头超声检查用于检测胃内镜黏膜下剥离术后溃疡处的血流情况。
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New Techniques to Control Gastrointestinal Bleeding.
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