Sharma A K, Shukla A K, Prabhakar G, Sarin Y K, Sharma C S
Department of Pediatric Surgery, SMS Medical College & Attached SPMCHI, Jaipur, India.
Int Surg. 1993 Oct-Dec;78(4):311-4.
During a period of two decades, 1972-1991, 303 patients with esophageal atresia and/or tracheo-esophageal fistula were treated at the department of Pediatric Surgery, SMS Medical College, Jaipur, India. More than half of our patients fall into Waterston's risk category C. To evaluate the improvement in our results, the patients were divided into four phases of 5 years each. Over the period of observation, the incidence of new cases as well as the number of associated anomalies has considerably increased. With time, more patients are being diagnosed and referred early for treatment. This has resulted in more patients being treated by primary repair with or without a gastrostomy. Extrapleural approach and single layer end-to-end anastomosis has been practised in all cases. Results have shown a steady improvement primarily because of early recognition, improved perioperative care and newer antibiotics. Although postoperative pulmonary complications and anastomotic leak have shown a decreasing trend, but the presence of severe associated anomalies, pulmonary complications and sepsis still remain the major killers in our set-up. Although our results may not match those from the developed countries, we have still come a long way, improving our overall survival rate of 4.6% in 1972-76 to 45.7% in 1987-91. Through the present article, we wish to highlight the practical problems faced in the management of these patients in underprivileged developing countries.
在1972年至1991年的二十年期间,印度斋浦尔SMS医学院小儿外科治疗了303例食管闭锁和/或气管食管瘘患者。我们超过半数的患者属于沃斯顿风险分类C类。为评估我们治疗结果的改善情况,将患者分为四个阶段,每个阶段5年。在观察期间,新病例的发病率以及相关畸形的数量大幅增加。随着时间的推移,越来越多的患者被早期诊断并转诊接受治疗。这使得更多患者接受了有或没有胃造口术的一期修复治疗。所有病例均采用胸膜外入路和单层端端吻合术。结果显示有稳步改善,这主要归功于早期识别、改善的围手术期护理和更新的抗生素。虽然术后肺部并发症和吻合口漏呈下降趋势,但严重相关畸形、肺部并发症和脓毒症的存在仍然是我们治疗中的主要致死因素。尽管我们的结果可能无法与发达国家的结果相匹配,但我们仍然取得了很大进展,将1972 - 1976年4.6%的总生存率提高到了1987 - 1991年的45.7%。通过本文,我们希望强调在贫困的发展中国家管理这些患者时面临的实际问题。