The influence of UV irradiation on vitamin D metabolism in children with chronic renal diseases.

The aim of this study was to find out whether an improvement of vitamin D metabolism and its metabolites and a decrease of parathormones can be reached through a diet and UV irradiation. Forty-eight children with kidney insufficiency were divided into four groups: Group 1--diet according to Bergström with EAA and cetoanalogue supplementation plus UV therapy; Group 2--diet plus EAA and cetoanalogue supplementation without UV therapy; Group 3--without diet and supplementation of EAA and ceto but with UV therapy; Group 4--without any diet and without UV therapy. The average levels of kidney insufficiency in all children at the stage of a manifest kidney insufficiency were not significantly different. As a result it became obvious that children exposed to UV irradiation with or without a diet had better post-treatment values and that children with kidney insufficiency reacted to UV therapy plus diet best of all. One can obtain the same results also by oral vitamin D therapy, although we have to point out the danger of calcinosis and stone formation which the author could frequently demonstrate, but never after UV treatment.