Larrazet F S, Dupouy P J, Rande J L, Hirosaka A, Kvasnicka J, Geschwind H J
University Hospital Henri-Mondor, University of Paris XII, Créteil, France.
J Am Coll Cardiol. 1994 May;23(6):1321-6. doi: 10.1016/0735-1097(94)90373-5.
Percutaneous intracoronary angioscopy was used to study the morphologic changes occurring in coronary arteries after balloon or laser angioplasty.
Angioscopy is thought to provide details of the coronary vessel lumen and the inner wall.
Coronary lesions were studied in 44 patients with a 4.5F Imagecath angioscope before and after each interventional procedure. Balloon and laser angioplasty were performed in 21 (group I) and 23 patients (group II), respectively. There was no difference in age, gender or angiographic lesion appearance before the procedure between the two groups.
Circumferential visualization of the target lesion was successfully completed in 17 group I and 19 group II patients. A larger lumen than that observed at baseline was seen in all 17 group I and in 13 of the 19 group II patients. Tissue remnants were observed in all group I and II patients. Laser irradiation resulted in characteristic sharp-edged craters. Dissection was identified in 2 of 19 patients before versus 9 of 19 patients after balloon angioplasty (p < 0.05) and in 0 of 23 patients before versus 4 of 23 patients after laser angioplasty (p = NS). Subintimal hemorrhage was observed in 3 of 19 patients before versus 11 of 19 patients after balloon angioplasty (p < 0.05) and in 2 of 23 patients before versus 4 of 23 patients after laser angioplasty (p = NS). The frequency of hemorrhage was higher in group I than in group II (11 of 19 vs. 4 of 23, respectively, p < 0.02).
Angioscopy provides valuable information on lesion morphology after coronary interventions. Balloon dilation results in a high rate of dissection and subintimal hemorrhage. Laser angioplasty is able to ablate obstructing tissue and results in a lower rate of subintimal hemorrhage than balloon dilation.
采用经皮冠状动脉血管镜检查,研究球囊血管成形术或激光血管成形术后冠状动脉发生的形态学变化。
血管镜检查被认为可提供冠状动脉管腔和内壁的详细情况。
使用4.5F Imagecath血管镜,在44例患者每次介入操作前后对冠状动脉病变进行研究。分别对21例患者(第一组)进行球囊血管成形术,对23例患者(第二组)进行激光血管成形术。两组患者术前的年龄、性别或血管造影病变表现无差异。
第一组17例患者和第二组19例患者成功完成了目标病变的周向观察。第一组的所有17例患者以及第二组的19例患者中的13例,术后管腔均比基线时增大。在第一组和第二组的所有患者中均观察到组织残留。激光照射导致形成特征性的边缘锐利的火山口。球囊血管成形术前19例患者中有2例出现夹层,术后有9例(p < 0.05);激光血管成形术前23例患者中无夹层,术后有4例(p = 无显著性差异)。球囊血管成形术前19例患者中有3例出现内膜下出血,术后有11例(p < 0.05);激光血管成形术前23例患者中有2例出现内膜下出血,术后有4例(p = 无显著性差异)。第一组出血频率高于第二组(分别为19例中的11例和23例中的4例,p < 0.02)。
血管镜检查为冠状动脉介入术后的病变形态提供了有价值的信息。球囊扩张导致夹层和内膜下出血的发生率较高。激光血管成形术能够消融阻塞组织,且内膜下出血发生率低于球囊扩张。