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射频导管消融术治疗左、右心室起源的特发性心动过速。

Radiofrequency catheter ablation as a cure for idiopathic tachycardia of both left and right ventricular origin.

作者信息

Coggins D L, Lee R J, Sweeney J, Chein W W, Van Hare G, Epstein L, Gonzalez R, Griffin J C, Lesh M D, Scheinman M M

机构信息

Department of Medicine, University of California, San Francisco 94143.

出版信息

J Am Coll Cardiol. 1994 May;23(6):1333-41. doi: 10.1016/0735-1097(94)90375-1.

Abstract

OBJECTIVES

The purpose of this study was 1) to investigate the efficacy and safety of radiofrequency energy catheter ablation as curative treatment for idiopathic tachycardia of both left and right ventricular origin, and 2) to compare the usefulness of different methods used to map the site of origin of idiopathic ventricular tachycardia.

BACKGROUND

Percutaneous radiofrequency catheter ablation has been used with dramatic success in the treatment of patients with Wolff-Parkinson-White syndrome, atrioventricular node reentrant tachycardia and bundle branch reentrant tachycardia. Limited data are available on the use of radiofrequency energy catheter ablation as curative treatment for idiopathic tachycardia of both left and right ventricular origin.

METHODS

Twenty-eight consecutive patients (13 to 71 years old) presenting with idiopathic ventricular tachycardia were enrolled in the study. The site of origin of both left and right ventricular tachycardia was mapped using earliest endocardial activation times during tachycardia and by pace mapping. These mapping techniques were compared.

RESULTS

Radiofrequency ablation was successful in all eight patients (100%) with left ventricular tachycardia. Tachycardia recurred in one patient. The ablation procedure was complicated by mild aortic insufficiency in one patient. Right ventricular outflow tract tachycardia was successfully ablated in 17 (85%) of 20 patients. The success rate at follow-up was 85%. In one patient, the ablation procedure was complicated by acute ventricular perforation and death. Pace maps from successful ablation sites were better than pace maps from unsuccessful sites (p < 0.004). Endocardial activation times at successful ablation sites were not different from unsuccessful sites (p < 0.13).

CONCLUSIONS

Radiofrequency catheter ablation is an effective treatment for idiopathic ventricular tachycardia. The site of origin of tachycardia is best identified using pace mapping. Significant complications can occur and should be considered in the risk/benefit analysis for each patient.

摘要

目的

本研究的目的是1)研究射频能量导管消融术作为治疗左、右心室起源的特发性心动过速的疗效和安全性,以及2)比较用于标测特发性室性心动过速起源部位的不同方法的实用性。

背景

经皮射频导管消融术已成功用于治疗预激综合征、房室结折返性心动过速和束支折返性心动过速患者。关于射频能量导管消融术作为治疗左、右心室起源的特发性心动过速的疗效,现有数据有限。

方法

连续纳入28例(年龄13至71岁)患有特发性室性心动过速的患者。通过心动过速期间最早的心内膜激动时间和起搏标测来标测左、右心室心动过速的起源部位。对这些标测技术进行了比较。

结果

8例左心室心动过速患者全部(100%)成功进行了射频消融。1例患者心动过速复发。1例患者消融过程并发轻度主动脉瓣关闭不全。20例患者中有17例(85%)右心室流出道心动过速成功消融。随访成功率为85%。1例患者消融过程并发急性心室穿孔并死亡。成功消融部位的起搏标测优于未成功部位(p<0.004)。成功消融部位的心内膜激动时间与未成功部位无差异(p<0.13)。

结论

射频导管消融术是治疗特发性室性心动过速的有效方法。通过起搏标测能最好地确定心动过速的起源部位。可能会发生严重并发症,在对每位患者进行风险/获益分析时应予以考虑。

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