[角膜与合成抗疟药]
[The cornea and synthetic antimalarials].
作者信息
Jeddi A, Ben Osman N, Daghfous F, Bouguila H, Charfi O, Ayed S
机构信息
Institut Hédi Rais d'Ophtalmologie, Tunis, Tunisie.
出版信息
J Fr Ophtalmol. 1994;17(1):36-8.
PMID:8176172
Abstract
The main targets of antimalarial ocular toxicity are the cornea, ciliary body and retina. In sixty patients treated with chloroquine (Nivaquine) 73% showed keratopathy. The clinical features and clinical course of this keratopathy and its relationship with retinopathy were described. In contrast with retinopathy, keratopathy is not contraindication to antimalarial treatment.
摘要
抗疟药眼部毒性的主要靶器官是角膜、睫状体和视网膜。在60例接受氯喹（磷酸氯喹）治疗的患者中，73%出现了角膜病变。本文描述了这种角膜病变的临床特征、临床病程及其与视网膜病变的关系。与视网膜病变不同，角膜病变并非抗疟治疗的禁忌证。
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