Wahl R L, Helvie M A, Chang A E, Andersson I
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109-0028.
J Nucl Med. 1994 May;35(5):872-5.
The purpose of this study was to determine the feasibility of FDG-PET imaging in women with silicone implant augmentation mammoplasties where mammographic detection of breast cancers is challenging due to the implants' radiodensity, which can obscure tumor visualization.
FDG-PET imaging was performed in two women with augmentation mammoplasties and small palpable breast abnormalities. Mammograms with and without breast displacement were also performed.
PET clearly demonstrated focal FDG accumulation in the suspicious breasts, corresponding to tumors of less than 1.5 cm in diameter. There was no degradation of image quality by the implants and no need for breast displacement views. By contrast, implant displacement mammograms were necessary to fully delineate the tumors.
While mammograms with displacement views represent the initial choice for imaging the augmented breast, FDG-PET can image tumors in the augmented breast without implant displacement and without obvious degradation of image quality by the implant. FDG-PET warrants additional evaluation as an adjunctive study in the augmented breast, particularly when displacement mammographic views are not adequate or are impossible to perform due to peri-implant capsule formation.
本研究的目的是确定氟代脱氧葡萄糖正电子发射断层显像（FDG-PET）成像在接受硅胶植入隆乳术的女性中的可行性。在这类女性中，由于植入物的放射性密度会掩盖肿瘤显像，通过乳房X线摄影检测乳腺癌具有挑战性。
对两名接受隆乳术且乳房有可触及小异常的女性进行了FDG-PET成像。还进行了有和没有乳房移位的乳房X线摄影。
PET清楚地显示了可疑乳房中局灶性FDG积聚，对应于直径小于1.5厘米的肿瘤。植入物未导致图像质量下降，且无需乳房移位视图。相比之下，为了完全描绘肿瘤，需要进行植入物移位乳房X线摄影。
虽然有移位视图的乳房X线摄影是对隆乳乳房进行成像的首选，但FDG-PET可以在不移位植入物的情况下对隆乳乳房中的肿瘤进行成像，且植入物不会明显降低图像质量。FDG-PET作为对隆乳乳房的辅助检查值得进一步评估，特别是当移位乳房X线摄影视图不充分或由于植入物周围包膜形成而无法进行时。
