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[迷走神经副神经节瘤]

[Vagal paraganglioma].

作者信息

Miani S, Boneschi M, Erba M, Giordanengo F

机构信息

Istituto di Chirurgia Generale e Cadiovascolare, Università degli Studi di Milano.

出版信息

Minerva Chir. 1993 Dec;48(23-24):1449-53.

PMID:8177450
Abstract

Vagal paragangliomas are rare tumors of neural crest origin. This neoplasm is generally located at various points along the peripheral distribution of the vagus nerve, in the region of the jugular and nodose ganglia, just beneath the perineurium of the nerve, but may arise anywhere along the course of the vagus nerve. Histologically, vagal paragangliomas are similar to carotid body tumors, and occasionally can undergo malignant transformation and metastasize (10-19%) or infiltrate the base of the skull. Selective arteriography can distinguish vagal paraganglioma from carotid body tumor, because the first lies above carotid bifurcation without widening of the vessels. CT scanning and MR are useful for preoperative evaluation of the jugular foramen for neoplastic involvement. Surgical resection is the treatment of choice, but usually it isn't possible to exercise these lesions without sacrifice of the vagus nerve. A careful follow-up examination for the development of metastases and multicentric paragangliomas is necessary. Two cases of vagal paragangliomas one of them with cervical node metastases, are reported. Diagnostic and surgical features of these rare neoplasms are outlined.

摘要

迷走神经副神经节瘤是一种罕见的起源于神经嵴的肿瘤。这种肿瘤通常位于迷走神经外周分布的不同部位,在颈静脉节和结状神经节区域,恰好在神经束膜下方,但也可能出现在迷走神经行程的任何部位。组织学上,迷走神经副神经节瘤与颈动脉体瘤相似,偶尔可发生恶性转化并转移(10 - 19%)或侵犯颅底。选择性动脉造影可将迷走神经副神经节瘤与颈动脉体瘤区分开来,因为前者位于颈动脉分叉上方且血管无增宽。CT扫描和磁共振成像对术前评估颈静脉孔是否受肿瘤累及很有用。手术切除是首选治疗方法,但通常不牺牲迷走神经就无法处理这些病变。对转移和多中心副神经节瘤的发生进行仔细的随访检查是必要的。报告了两例迷走神经副神经节瘤,其中一例伴有颈部淋巴结转移。概述了这些罕见肿瘤的诊断和手术特点。

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