Marchesi M, Biffoni M, Tartaglia F, Nobili Benedetti R, Nuccio G, Jaus M O, Faloci C, Mastropietro T, Millarelli M, Campana F P
Istituto di III Clinica Chirurgica Generale e Terapia Chirurgica, Università degli Studi La Sapienza, Roma.
G Chir. 1997 Oct;18(10):615-8.
Cervical paragangliomas are uncommon benign or malignant neoplasms, originated from the stem cells of the neural crest. Up to date it is still not easy to define properly their biological behaviour, the possible multicentric location and the association with Multiple Endocrine Neoplasias. After a wide review of recent diagnostic, pathological and clinical notions, the Authors report their experience, from 1970 to 1995, of 10 patients affected by sporadic paraganglioma and 1 by familial multicentric neoplasm localized on carotid bodies of both sides, left vagus nerve and left hypoglossus nerve. All patients but one were treated by a curative resection of the neoplasm; in one case only an explorative laparotomy was possible because of the visceral and vascular involvement.
颈副神经节瘤是起源于神经嵴干细胞的罕见良性或恶性肿瘤。迄今为止,要准确界定其生物学行为、可能的多中心定位以及与多发性内分泌肿瘤的关联仍非易事。在广泛回顾近期的诊断、病理和临床概念后,作者报告了他们1970年至1995年间的经验,涉及10例散发性副神经节瘤患者以及1例家族性多中心肿瘤患者,后者肿瘤位于双侧颈动脉体、左侧迷走神经和左侧舌下神经。除1例患者外,所有患者均接受了肿瘤的根治性切除;有1例因内脏和血管受累,仅进行了探查性剖腹手术。