Boneschi M, Erba M, Giuffrida G F, Mattioli A, Miani S
Istituto di Chirurgia Generale e Cardiovascolare, Università degli Studi di Milano.
Minerva Chir. 1993 Dec;48(23-24):1455-8.
Functioning paraganglioma of the mediastinum is an uncommon tumor of the paraganglion system. We report a case of a 26 year-old woman with a 6 month history of hypertension refractory to therapy. Urinary catecholamine excretion and plasma noradrenaline concentration were elevated. Chest radiograph and computed tomography (CT) scan revealed high-density mass located on the posterior mediastinum. An mIBG scan showed uptake by the mediastinal tumor. At thoracotomy a 5 cm lesion was resected. Histological examination confirmed that it was a paraganglioma. Authors refer on the clinical finding and diagnostic procedures of this rare disease.
纵隔嗜铬细胞瘤是副神经节系统的一种罕见肿瘤。我们报告一例26岁女性患者,有6个月难治性高血压病史。尿儿茶酚胺排泄量及血浆去甲肾上腺素浓度升高。胸部X线片及计算机断层扫描(CT)显示后纵隔有高密度肿块。间碘苄胍(mIBG)扫描显示纵隔肿瘤有摄取。开胸手术切除了一个5厘米的病灶。组织学检查证实为嗜铬细胞瘤。作者介绍了这种罕见疾病的临床发现及诊断方法。