Murofushi T, Mizuno M, Hayashida T
Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Japan.
ORL J Otorhinolaryngol Relat Spec. 1994 Mar-Apr;56(2):83-6. doi: 10.1159/000276615.
We investigated the postcaloric nystagmus that is related to positional change in 24 patients with spinocerebellar degeneration (SCD) and compared it with that in normal subjects. Six ears of 3 patients exhibited no evaluable caloric response. In 42 ears of 21 patients, the primary phase of caloric nystagmus was definitely observed. In 37 of 42 (88%) ears, postcaloric nystagmus was observed. The postcaloric nystagmus from a positional change in patients with SCD was significantly larger than that in control subjects. Furthermore, it was significantly exaggerated in patients with brainstem and cerebellar lesions in comparison with patients with pure cerebellar lesions. The degree of disturbance coming from visual suppression had only a limited correlation with the exaggerated postcaloric nystagmus. Also discussed are possible other factors affecting the exaggerated postcaloric nystagmus.
我们对24例脊髓小脑变性(SCD)患者中与体位变化相关的冷热试验性眼震进行了研究,并将其与正常受试者的进行比较。3例患者的6只耳朵未表现出可评估的冷热反应。在21例患者的42只耳朵中,明确观察到了冷热试验性眼震的初级相。在42只耳朵中的37只(88%)观察到了冷热试验后眼震。SCD患者因体位变化产生的冷热试验后眼震明显大于对照组受试者。此外,与单纯小脑病变患者相比,脑干和小脑病变患者的该眼震明显更为夸张。视觉抑制引起的干扰程度与夸张的冷热试验后眼震仅有有限的相关性。还讨论了可能影响夸张的冷热试验后眼震的其他因素。