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[关节中的脂质微晶和其他罕见晶体]

[Lipid microcrystals and other rare crystals in the joints].

作者信息

Tourlière D, Benhamou C L

机构信息

Service de rhumatologie, CHR Orléans La Source.

出版信息

Rev Prat. 1994 Jan 15;44(2):197-200.

PMID:8178075
Abstract

Although not strictly of crystalline nature, various formations can be observed in joint fluids and be responsible for "microcrystalline" arthritis. They can consist of lipidic structures (cholesterol crystals, fatty lobules, liposomes) or calcium crystalline structures such as calcium oxalate crystals detected in fluids of dialyzed chronic renal failure patients, reflecting primary or secondary oxalosis. Other phosphate calcium crystals have been identified, associated to apatite or pyrophosphate crystals, but their pathogenic role is uncertain. Charcot-Leyden crystals reflect eosinophilic arthritis. A phylogenic role may be played by corticoid suspension crystal or prosthetic debris. Lastly, some crystals can be artefacts, resulting from sampling conditions and storage of joint fluids.

摘要

尽管并非严格意义上的晶体性质,但在关节液中可观察到各种沉积物,并导致“微晶”关节炎。它们可以由脂质结构(胆固醇晶体、脂肪小叶、脂质体)或钙晶体结构组成,如在慢性肾衰竭透析患者的液体中检测到的草酸钙晶体,反映原发性或继发性草酸中毒。已鉴定出其他磷酸钙晶体,与磷灰石或焦磷酸晶体有关,但其致病作用尚不确定。夏科-莱登晶体反映嗜酸性关节炎。皮质类固醇混悬晶体或假体碎片可能起系统发生作用。最后,一些晶体可能是假象,由关节液的采样条件和储存导致。

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