Hinghofer-Szalkay H, Noskov V B
Arbeitsgruppe für Volumenregulation und Weltraummedizin, Karl-Franzens-Universität, Graz, Osterreich.
Wien Med Wochenschr. 1993;143(23-24):626-9.
We performed an experiment within the 1991 Austromir mission, 3 months preflight, on the 6th inflight and 4th postflight days, respectively. Primary goal was to measure changes in venous blood and plasma sound velocity (BSV, PSV) with lower body suction (LBNP). Contrasting earth-based findings, there was no increase in BSV nor PSV with LBNP inflight. Postflight, the elevation in both values was greater than expected. Taken together with LBNP data from the German 1992 Mir cosmonaut, we propose the hypothesis that the dynamics of tissue fluid exchange is profoundly influenced by m-g adaptation. A further goal of the experiment was to determine volume- and stress-sensitive hormones. The results need validation by additional flight data and might be considered as an important contribution to our understanding of the normal functioning and pathophysiology of the interstitial organ.
我们分别在1991年“奥斯特米尔”任务的飞行前3个月、飞行中第6天和飞行后第4天进行了一项实验。主要目标是通过下体负压（LBNP）测量静脉血和血浆声速（BSV、PSV）的变化。与地面研究结果相反，飞行中下体负压并未使BSV和PSV增加。飞行后，这两个数值的升高幅度大于预期。结合来自1992年德国和平号空间站宇航员的下体负压数据，我们提出一个假说：组织液交换动力学受到微重力适应的深刻影响。该实验的另一个目标是确定对容量和压力敏感的激素。这些结果需要更多飞行数据的验证，并且可能被视为对我们理解间质器官正常功能和病理生理学的重要贡献。
