Ogihara M, Takaiwa M, Yanagida T, Koseki K
Department of Urology, Yonezawa City Hospital.
Hinyokika Kiyo. 1994 Mar;40(3):225-7.
A 61-year-old man with left renal artery embolus was treated with a continuous selective intra-arterial urokinase (UK) infusion therapy. UK was administered through a 5 Fr. catheter embedded into the occlusive segment of the artery selectively. Continuous low dose UK (15,000 units/hour) was infused following short-term ultra-high dose UK (480,000 units/60 min) infusion. A complete recanalization of the occluded artery was observed by day 7 and also no serious complications were noted during the treatment. Thus, a continuous selective intra-arterial UK infusion therapy seemed to be more effective than conventional methods, especially in patients with complete obstruction.
一名61岁的左肾动脉栓塞男性患者接受了持续选择性动脉内尿激酶(UK)输注治疗。通过一根选择性嵌入动脉闭塞段的5F导管给予尿激酶。在短期超高剂量尿激酶(480,000单位/60分钟)输注后,持续低剂量输注尿激酶(15,000单位/小时)。到第7天时观察到闭塞动脉完全再通,并且治疗期间未发现严重并发症。因此,持续选择性动脉内尿激酶输注治疗似乎比传统方法更有效,特别是对于完全阻塞的患者。