Swisher L A, Roberts J R, Glynn M J
Department of Emergency Medicine, Mercy Catholic Medical Center, Philadelphia, PA.
Am J Emerg Med. 1994 May;12(3):343-6. doi: 10.1016/0735-6757(94)90156-2.
Eikenella corrodens, a fastidious, slow-growing, gram-negative, facultative anaerobic bacillus may be encountered in wounds exposed to human saliva, especially human bites and head and neck infections. An unusual case of a mixed flora E corrodens and Streptococcus septic arthritis with adjacent osteomyelitis secondary to saliva contamination from licking an intravenous (i.v.) needle is presented. A literature search showed 53 previous cases of E corrodens infections in i.v. drug users. However, none of these infections affected bones or joints. The microbiology and unusual antibiotic sensitivity are presented. Recommendations for treatment include penicillin or ampicillin. Tetracycline is recommended in the penicillin-allergic patient. This is the first case that draws attention to the connection between E corrodens, i.v. drug use, and septic arthritis and osteomyelitis.
腐蚀埃肯菌是一种苛求、生长缓慢、革兰氏阴性、兼性厌氧的杆菌，在暴露于人类唾液的伤口中可能会遇到，尤其是人咬伤以及头颈部感染。本文报告了一例不寻常的病例，由于舔静脉注射（i.v.）针头导致唾液污染，出现了腐蚀埃肯菌与链球菌混合菌群引起的化脓性关节炎并伴有相邻骨髓炎。文献检索显示，此前有53例静脉注射吸毒者感染腐蚀埃肯菌的病例。然而，这些感染均未累及骨骼或关节。本文介绍了该病例的微生物学特征及异常的抗生素敏感性。治疗建议包括使用青霉素或氨苄西林。对青霉素过敏的患者建议使用四环素。这是首例引起人们关注腐蚀埃肯菌、静脉注射吸毒与化脓性关节炎及骨髓炎之间联系的病例。
