Tsuji J, Ito J, Naito Y, Honjo I
Department of Otolaryngology, Faculty of Medicine, Kyoto University, Japan.
Eur Arch Otorhinolaryngol. 1994;251(1):48-51. doi: 10.1007/BF00175957.
The influence of caloric stimulation on the primary vestibular fibers originating from the otolith organ was investigated in the guinea pig. Firing rates were recorded from single vestibular neurons in the superior vestibular (Scarpa's) ganglion which were identified physiologically as originating from the otolith organs, mainly from the utricles. Eighty-six percent of the neurons responded to caloric stimulation. Neurons with a high coefficient of variation of firing regularity reacted more sensitively to tilting and also had a tendency to react more sensitively to caloric stimulation. There was a tendency for neurons with increased firing rates in response to ipsilateral tilting to have increased firing rates to warm stimulation, while neurons whose rates increased to contralateral tilting had increased firing rates to cold stimulation. These results indicate that the otolith organs have the same unidirectional tendency to caloric simulation with results comparable to optimal tilting directions.
在豚鼠中研究了热量刺激对源自耳石器官的初级前庭纤维的影响。从前庭上神经节（斯卡帕神经节）的单个前庭神经元记录放电率，这些神经元在生理上被确定为源自耳石器官，主要来自椭圆囊。86%的神经元对热量刺激有反应。放电规律性变异系数高的神经元对倾斜反应更敏感，对热量刺激也有更敏感的倾向。对同侧倾斜反应时放电率增加的神经元，对温热刺激的放电率有增加的趋势，而对侧倾斜时放电率增加的神经元，对冷刺激的放电率有增加的趋势。这些结果表明，耳石器官对热量模拟具有相同的单向倾向，其结果与最佳倾斜方向相当。
