Ramsay A D, Rooney N
University Pathology, University of Southampton, UK.
Eur J Cancer B Oral Oncol. 1993 Apr;29B(2):99-102. doi: 10.1016/0964-1955(93)90029-e.
Nasofacial T-cell lymphoma includes diseases otherwise called "lethal midline granuloma" and "necrosis with atypical cells". It is characterised by relentless destruction of nose and palate in particular but the lymphoma remains localised to the head and neck. The age of onset ranges from 10 to 87 and the survival ranges from a few months to several years. The histological appearances are of a polymorphic infiltrate but including atypical T cells in a background of macrophages. There is a strong association with Epstein-Barr virus infection.
鼻面部T细胞淋巴瘤包括其他被称为“致死性中线肉芽肿”和“伴有非典型细胞的坏死”的疾病。其特征是尤其对鼻子和上颚进行持续性破坏，但淋巴瘤仍局限于头颈部。发病年龄范围为10至87岁，生存期从几个月到几年不等。组织学表现为多形性浸润，但在巨噬细胞背景中包括非典型T细胞。与爱泼斯坦-巴尔病毒感染有很强的关联。
