Champoux A N, Del Beccaro M A, Nazar-Stewart V
Department of Pediatrics, University of Washington, Seattle.
Arch Pediatr Adolesc Med. 1994 May;148(5):474-8. doi: 10.1001/archpedi.1994.02170050032006.
To determine the risk factors associated with recurrent intussusception (RI) and to characterize the timing, features, and complications of RI.
Retrospective chart review.
Children's Hospital and Medical Center, Seattle, Wash.
All patients with a diagnosis of intussusception who underwent barium enema as treatment for reduction between October 1, 1979 and December 31, 1990. Children with RI (N = 23, seven with two or more recurrent episodes) were classified as the case group; children with a single intussusception (N = 234), controls.
There were no statistically significant differences in age, sex, race, symptoms, duration of symptoms, or results of the physical examination between the case group and controls. Reduction of the initial intussusception by a barium enema occurred in 96% of patients in the case group vs 62% of the controls (odds ratio, 13.50; 95% confidence intervals, 2.10 to 563.4; P = .003). Only one of 33 episodes of RI followed an operative reduction. In comparing the first recurrent episode with the initial episode, there was a significant reduction in the proportion of patients presenting with lethargy (0% vs 30%; Fisher Exact Test, P = .009) or blood in the stool (5% vs 52%; P < .002) and a drop in the median duration of symptoms from 20 to 6 hours.
Recurrent intussusception cannot be predicted by presenting features or symptoms; operative reduction due to a failed reduction by a barium enema reduces the risk of RI; and patients with RI have fewer symptoms with a shorter duration.
确定与复发性肠套叠(RI)相关的危险因素,并描述RI的发生时间、特征及并发症。
回顾性病历审查。
华盛顿州西雅图儿童医院及医疗中心。
1979年10月1日至1990年12月31日期间,所有诊断为肠套叠并接受钡剂灌肠复位治疗的患者。RI患儿(n = 23例,其中7例有两次或更多次复发)被归为病例组;单发肠套叠患儿(n = 234例)为对照组。
病例组与对照组在年龄、性别、种族、症状、症状持续时间或体格检查结果方面无统计学显著差异。病例组96%的患者通过钡剂灌肠成功复位初始肠套叠,而对照组为62%(优势比为13.50;95%置信区间为2.10至563.4;P = 0.003)。33次RI发作中只有1次发生在手术复位后。将首次复发发作与初始发作进行比较,出现嗜睡的患者比例显著降低(0%对30%;Fisher精确检验,P = 0.009)或便血的患者比例显著降低(5%对52%;P < 0.002),症状持续时间中位数从20小时降至6小时。
无法通过临床表现或症状预测复发性肠套叠;因钡剂灌肠复位失败而进行手术复位可降低RI风险;RI患者症状较少,持续时间较短。