Bodner L, Kaffe I, Cohen Z, Dayan D
Department of Oral and Maxillofacial Surgery, Tel Aviv University, Israel.
Dentomaxillofac Radiol. 1993 Nov;22(4):195-8. doi: 10.1259/dmfr.22.4.8181646.
The study evaluates radiographically the long-term changes that occur during the healing of tooth sockets in a desalivated rat model. Experimental rats underwent sialadenectomy of the submandibular and sublingual glands and ligation of the parotid ducts. Mandibular left first molars were extracted and the rats killed at 0, 14, 21, 28, 45 and 60 days post-extraction. The mandibles were removed, cleaned of soft tissue, placed on a size 2 dental X-ray film and exposed together with an aluminium stepwedge 0.5-3.0 mm. Socket density was measured using a digital densitometer and related to the equivalent density of aluminium. The density of the image of the apical area of the socket was similar in control and desalivated groups (P > 0.05) throughout the study. However, the density of the image of the crestal area of the socket was lower (P < 0.01-0.001) between days 21 and 60 in desalivated rats. This suggests that desalivation causes a long-term delay in socket healing.
该研究通过影像学评估去涎大鼠模型中牙槽窝愈合过程中发生的长期变化。实验大鼠接受了下颌下腺和舌下腺的涎腺切除术以及腮腺导管结扎术。拔除下颌左侧第一磨牙，并在拔牙后0、14、21、28、45和60天处死大鼠。取出下颌骨，清除软组织，放置在2号牙科X线片上，并与0.5 - 3.0毫米的铝阶梯楔形板一起曝光。使用数字密度计测量牙槽窝密度，并与铝的等效密度相关。在整个研究过程中，对照组和去涎组牙槽窝根尖区图像的密度相似（P > 0.05）。然而，在去涎大鼠中，牙槽窝嵴顶区图像的密度在第21天至60天之间较低（P < 0.01 - 0.001）。这表明去涎会导致牙槽窝愈合长期延迟。
