Maekawa K, Ohnishi H, Hirase T, Yamada T, Matsuo T
Department of Internal Medicine, Hyogo Prefectural Awaji Hospital, Sumoto, Japan.
J Intern Med. 1994 May;235(5):489-92. doi: 10.1111/j.1365-2796.1994.tb01108.x.
A 33-year-old pregnant woman suffered from acute anteroseptal myocardial infarction at the 19th gestational week. Despite periodic attacks of myocardial ischaemia after admission, the coronary arteriograms under the use of nitroglycerin were normal. Thereafter, she remained free from the ischaemic events with diltiazem hydrochloride and delivered a healthy baby. The coronary arteriography at puerperium also showed no organic narrowing. However, the provocative test with acetylcholine chloride caused severe spasm of the left anterior descending coronary artery. These findings strongly suggest that acute myocardial infarction in this pregnant woman was caused by coronary artery spasm.
