Ray D, Abel R
Department of Chest Diseases, Christian Medical College, Vellore, India.
J Trop Pediatr. 1994 Feb;40(1):49-51. doi: 10.1093/tropej/40.1.49.
During the period of 1981-82 in a survey of 21 schools in four villages of North Arcot Ambedkar District of Tamil Nadu, amongst a population of 4282 children we detected 92 with respiratory symptoms and blood eosinophilia greater than 1000 per cumm. Sixty-eight students had associated worn infestation, majority with hookworm followed by giardia. Altogether 37 children had blood eosinophilia above 2000 per cumm and had symptoms of cough, dyspnoea, and wheeze consistent with pulmonary eosinophilia. Fourteen of the children with pulmonary eosinophilia had eosinopenic remission with deworming alone. Six of them, on the other hand, responded to diethyl carbamazine (DEC) alone and 17 others, following deworming, required further DEC therapy for successful eosinopenic remission, thus warranting a diagnosis of Tropical Pulmonary Eosinophilia (TPE).
1981 - 1982年期间，在泰米尔纳德邦北阿尔果德安贝德卡尔区四个村庄的21所学校进行的一项调查中，在4282名儿童中，我们发现92名有呼吸道症状且血液嗜酸性粒细胞计数高于每立方毫米1000。68名学生伴有蠕虫感染，多数感染钩虫，其次是贾第虫。共有37名儿童血液嗜酸性粒细胞计数高于每立方毫米2000，并有咳嗽、呼吸困难和喘息症状，符合肺嗜酸性粒细胞增多症。14名患有肺嗜酸性粒细胞增多症的儿童仅通过驱虫就实现了嗜酸性粒细胞减少缓解。另一方面，其中6名儿童仅对乙胺嗪（DEC）有反应，另外17名儿童在驱虫后需要进一步的DEC治疗才能成功实现嗜酸性粒细胞减少缓解，因此需要诊断为热带肺嗜酸性粒细胞增多症（TPE）。
