Saitoh K, Motegi R, Hirabayashi Y, Shimizu R
Department of Anesthesiology, Jichi Medical School, Tochigi.
Masui. 1994 Mar;43(3):388-91.
A 24-year-old pregnant woman was scheduled for Caesarean section during the 31st week of pregnancy. The patient had been treated with MgSO4 for premature labor and toxemia. During anesthesia, cardiac arrest occurred twice. The first cardiac arrest occurred immediately after induction of anesthesia and seemed to be due to combined effects of hypermagnesemia, thiopental and supine hypotensive syndrome. Three babies were delivered during cardiac massage. The second one occurred immediately after administration of methyl-ergometrine malate and seemed to be due to combined effects of hypermagnesemia and methyl-ergometrine malate. The patient and three babies did not develop any complication. In giving anesthesia for patients with hypermagnesemia, anesthetists should take account of interactions between magnesium, anesthetics and other drugs.
一名24岁孕妇在妊娠31周时计划进行剖宫产。该患者曾因早产和毒血症接受硫酸镁治疗。麻醉期间发生了两次心脏骤停。第一次心脏骤停发生在麻醉诱导后立即出现，似乎是高镁血症、硫喷妥钠和仰卧位低血压综合征共同作用的结果。在心脏按压期间娩出了三个婴儿。第二次发生在给予马来酸麦角新碱后立即出现，似乎是高镁血症和马来酸麦角新碱共同作用的结果。患者和三个婴儿均未出现任何并发症。在为高镁血症患者实施麻醉时，麻醉医生应考虑镁、麻醉剂和其他药物之间的相互作用。
