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癫痫发作的行为治疗及癫痫发作的抑制

The behavioral treatment of epilepsy generation and inhibition of seizures.

作者信息

Fenwick P

机构信息

Department of Neuropsychiatry, Maudsley Hospital, London, England.

出版信息

Neurol Clin. 1994 Feb;12(1):175-202.

PMID:8183209
Abstract

These studies provide abundant evidence of the close interrelation between seizure activity and behavior. They reaffirm the point that epileptic seizures do not occur in a behavioral vacuum and strengthen the theoretical framework for behavioral treatment of epilepsy patients. As our understanding of the epileptic focus and its connections to surrounding cerebral systems increases, the concept that seizure control is significantly influenced by altering behavior of the patient becomes more comprehensible. Epileptic seizures should not be thought of as arising randomly. They occur in focal seizures when the pools of neurons surrounding the epilepsy focus are sufficiently excited for seizure activity to spread. Generalized seizures occur when the level of cortical excitability, or corticoreticular excitation, has reached a point at which thalamic recruiting volleys generalize and start to spread. In the partial epilepsies, a detailed clinical history should be taken as to the nature and characteristics of the aura and the form that seizure generalization or spread may take. Charting events surrounding the time of the seizure as described below are the engine which drives the creation of a countermeasure and its application to stopping seizures. They are the heart of a behavioral program and skill in interpreting the data will be repaid by the finding of the appropriate countermeasures for seizure reduction. This information will define those aspects of the patient's psychic life or behavior that will both trigger and inhibit seizure activity. Discussing this information with the patient will help him or her to understand that their seizures are not necessarily random events, but are intimately related to feelings, actions, and thoughts. A complete treatment of epilepsy involves not just medication, but includes teaching the patient about their brain and its functioning, and how they can use their feelings, thinking, and behavior in the control of their epilepsy.

摘要

这些研究提供了大量证据,证明癫痫发作活动与行为之间存在密切的相互关系。它们重申了癫痫发作并非发生在行为真空中这一观点,并加强了癫痫患者行为治疗的理论框架。随着我们对癫痫病灶及其与周围脑系统连接的了解不断增加,通过改变患者行为能显著影响癫痫控制这一概念变得更容易理解。癫痫发作不应被认为是随机发生的。局灶性发作是当癫痫病灶周围的神经元池被充分激发,使癫痫活动得以扩散时发生的。全身性发作则是当皮质兴奋性水平或皮质网状兴奋达到一定程度,此时丘脑募集性冲动泛化并开始扩散。在部分性癫痫中,应详细了解先兆的性质和特征以及癫痫发作泛化或扩散可能采取的形式等临床病史。如下所述,记录癫痫发作时刻周围的事件是推动制定对策并将其应用于阻止癫痫发作的动力。它们是行为计划的核心,解读这些数据的技巧将通过找到减少癫痫发作的适当对策而得到回报。这些信息将确定患者心理生活或行为中那些既能引发又能抑制癫痫活动的方面。与患者讨论这些信息将有助于他或她明白,他们的癫痫发作不一定是随机事件,而是与情感、行动和思想密切相关。癫痫的完整治疗不仅包括药物治疗,还包括教导患者了解他们的大脑及其功能,以及他们如何利用自己的情感、思维和行为来控制癫痫。

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