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用于颈动脉动脉瘤栓塞的正丁基-2-氰基丙烯酸酯。

N-butyl-2-cyanoacrylate for embolisation of carotid aneurysm.

作者信息

Teng M M, Chen C C, Lirng J F, Chen S S, Lee L S, Chang T

机构信息

Department of Radiology, Veterans General Hospital, Taipei, Taiwan, Republic of China.

出版信息

Neuroradiology. 1994;36(2):144-7. doi: 10.1007/BF00588084.

Abstract

We report the use of an N-butyl-2-cyanoacrylate (NBCA) mixture for embolisation of six cases of carotid aneurysm after detachable balloons, and/or microcoils had been placed in the aneurysm. The mixture was injected into the aneurysm to prevent delayed bleeding or distal migration of the balloons, or microcoils. No subarachnoid haemorrhage or distal migration of the balloons or microcoils occurred up to 4.5 years after embolisation. Reflux of the NBCA mixture into the parent artery occurred in one patient, who had a neurological deficit which recovered in a month. NBCA mixture may be useful in embolisation of intracranial or skull base arterial aneurysms, for reducing the size of remaining lumen in an aneurysm at high risk of rebleeding which accommodate no more balloons or microcoils, or preventing possible delayed migration of balloons or microcoils. However, prevention of leakage of the mixture into the parent artery remains a problem.

摘要

我们报告了在6例颈动脉动脉瘤患者中,在已将可脱性球囊和/或微线圈置入动脉瘤后,使用N-丁基-2-氰基丙烯酸酯(NBCA)混合物进行栓塞的情况。将该混合物注入动脉瘤以防止延迟出血或球囊或微线圈向远端移位。栓塞后长达4.5年,未发生蛛网膜下腔出血或球囊或微线圈向远端移位。1例患者出现NBCA混合物反流至供血动脉,该患者有神经功能缺损,1个月后恢复。NBCA混合物可能有助于颅内或颅底动脉动脉瘤的栓塞,用于减小再出血高风险且无法再容纳球囊或微线圈的动脉瘤内剩余管腔的大小,或防止球囊或微线圈可能出现的延迟移位。然而,防止混合物漏入供血动脉仍然是一个问题。

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