Allogeneic iliac transplants in rhesus monkeys. A sequential histologic study.

Fresh and frozen allogeneic iliac grafts were used in surgically prepared intraosseous defects. Four adult rhesus monkeys provided 19 specimens from 0 to 56 days postoperative. There were 8 specimens for each type of graft and 3 others used as controls. Histologic sections from each specimen were prepared and a description of the sequential healing events was given. The similarities and differences in repair were discussed. The advantages and disadvantages of each technique were analyzed and insight into their clinical applications was provided. No significant difference was observed in the sequential healing of the fresh and frozen allogeneic bone grafts, and both allografts induced a more rapid osseous regeneration than the controls. The fresh and frozen allogeneic transplants were accepted by the host as was evidenced by the involucrum formations.