Krywanio M L
St. Louis Children's Hospital, MO.
Nurs Res. 1994 May-Jun;43(3):133-7.
A meta-analysis of 37 studies on the effects of an intervention program on physiological development of the premature infant was conducted using multidisciplinary research reported since 1979. Two homogeneous populations based on mean infant birth weight were found in which infant stimulation programs were shown to be effective in enhancing physiological development (Group I: mean birth weight = 1,260 g, mean combined effect size = 1.54, SD = 0.54, 95% confidence interval = 1.22-1.86; Group II: mean birth weight = 1,524 g, mean combined ES = 0.51, SD = 0.30, 95% confidence interval = 0.39-0.63). The robustness of Group I was tentative based on the lack of small sample-small effect nonsignificant result studies discovered in the funnel plot. Group II results (based upon 1,306 infants) are a stronger indication that, in general, infants with birth weights greater than 1,500 g are positively affected by the initiation of a stimulation program during hospitalization.
自1979年以来，利用多学科研究对37项关于干预项目对早产儿生理发育影响的研究进行了荟萃分析。根据婴儿平均出生体重发现了两个同质群体，其中婴儿刺激项目被证明对促进生理发育有效（第一组：平均出生体重=1260克，平均综合效应量=1.54，标准差=0.54，95%置信区间=1.22 - 1.86；第二组：平均出生体重=1524克，平均综合效应量=0.51，标准差=0.30，95%置信区间=0.39 - 0.63）。基于漏斗图中未发现小样本 - 小效应无显著结果的研究，第一组的稳健性是初步的。第二组的结果（基于1306名婴儿）更有力地表明，一般来说，出生体重超过1500克的婴儿在住院期间开始接受刺激项目会受到积极影响。
