Rothacker D, Knolle J, Stiller D, Borchard F
Center of Pathology, Heinrich-Heine-University Düsseldorf, Germany.
Pathol Res Pract. 1993 Dec;189(10):1195-204. doi: 10.1016/S0344-0338(11)80844-7.
We present two rare cases of retroperitoneal mucinous cystadenomas (RMC) by clinical data, light microscopy, electron microscopy, histochemistry, and immunohistochemistry. Both tumors occurred in women. We excluded attachment to any organ. Additional immunohistochemical examinations were performed for comparison in 10 cases of ovarian mucinous cystadenomas (OMC). Both RMC showed no significant immunohistochemical differences from the OMC. Ultrastructurally and histologically the RMC resemble OMC reported in the literature. Immunohistologically, we proved gastric epithelial differentiation by using one monoclonal antibody (2B5) recognizing gastric mucin and one polyclonal antibody against pepsinogen II (PG II). In spite of this, the histogenesis of RMC in the presented cases in the end remains uncertain.
我们通过临床资料、光学显微镜、电子显微镜、组织化学和免疫组织化学方法，展示了两例罕见的腹膜后黏液性囊腺瘤（RMC）。这两个肿瘤均发生于女性。我们排除了与任何器官的附着关系。另外对10例卵巢黏液性囊腺瘤（OMC）进行了免疫组织化学检查以作比较。两个RMC在免疫组织化学方面与OMC均无显著差异。在超微结构和组织学上，RMC与文献报道的OMC相似。在免疫组织学方面，我们通过使用一种识别胃黏蛋白的单克隆抗体（2B5）和一种抗胃蛋白酶原II（PG II）的多克隆抗体，证实了胃上皮分化。尽管如此，所呈现病例中RMC的组织发生最终仍不确定。
