Boorstein J M, Wong K T, Grossman R I, Bolinger L, McGowan J C
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
Radiology. 1994 Jun;191(3):799-803. doi: 10.1148/radiology.191.3.8184068.
To study solitary metastatic lesions of the brain with routine spin-echo (SE) and magnetization transfer (MT) magnetic resonance (MR) imaging.
In 15 patients with such lesions, the MT ratio (MTR) was calculated in the center and at the periphery of the metastatic lesion, and distally in adjacent white matter, from the periphery of the lesion radially to the most distant cortex. It also was calculated for mirror-image locations in the opposite hemisphere to provide control values.
MTRs were decreased in and immediately around the site of the metastatic focus. MTRs also were lower than control values far distal to the metastatic focus, even when no abnormality was seen on SE MR images obtained before and those obtained after administration of gadopentetate dimeglumine.
MT enables demonstration of white matter abnormalities in patients with metastatic lesions not seen on SE MR images. These changes can be found in white matter far distal to the lesion and surrounding areas of edema.
采用常规自旋回波（SE）和磁化传递（MT）磁共振（MR）成像研究脑内孤立性转移瘤。
对15例患有此类病变的患者，在转移瘤中心、周边以及从瘤周径向至最远处皮质的相邻白质远端计算MT比率（MTR）。还在对侧半球的镜像位置计算MTR以提供对照值。
转移瘤灶及其紧邻区域的MTR降低。即使在静脉注射钆喷酸葡胺前后获得的SE MR图像上未发现异常，转移瘤灶远端的MTR也低于对照值。
MT能够显示出SE MR图像上未发现的转移瘤患者白质异常。这些改变可在远离瘤灶的白质以及水肿周围区域发现。
