Serious suppurative group A beta-hemolytic streptococcal infection in previously well children: report of six cases.

Recently, among adults and children, an increase in the incidence of invasive disease caused by group A beta hemolytic streptococcus (GABHS) has been noted. From December 6, 1981 to January 19, 1991, we experienced six cases of serious infection caused by GABHS in previously well children. Among them, five cases were found in recent two years. The clinical manifestations were varied. One child had sepsis, one had streptococcal toxic shock-like syndrome, two had pyogenic arthritis, and the other two newborn infants had empyema and cellulitis associated with sepsis. Early diagnosis and treatment with appropriate antibiotic are necessary for a good outcome. In addition, empyema and pyoarthritis of the hip often need surgical drainage.