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[在各种脑缺氧保护技术下严重脑外伤中的生物胺代谢]

[Biogenic amine metabolism in severe brain trauma during various techniques of brain protection from hypoxia].

作者信息

Usenko L V, Kligunenko E N

出版信息

Anesteziol Reanimatol. 1993 Nov-Dec(6):51-6.

PMID:8185076
Abstract

Biogenic amine metabolism in severe brain trauma has been analysed in 165 patients whose brain was protected from hypoxia with GOBA and thiobarbiturates in subnarcotic doses (116 cases) and the combination of the above agents with an early course of HBO (49 cases). The peculiarities of biogenic amine metabolism have been established in patients recovered and those who died later. As any activation of biogenic amine systems realizing stress enhances disadaptation processes, it is recommended to begin a course of HBO upon their stabilization.

摘要

对165例重度脑外伤患者的生物胺代谢进行了分析,这些患者的大脑通过使用戈贝酯(GOBA)和亚麻醉剂量的硫代巴比妥酸盐(116例)以及上述药物与早期高压氧(HBO)疗程联合使用(49例)来预防缺氧。已确定康复患者和后来死亡患者生物胺代谢的特点。由于实现应激的生物胺系统的任何激活都会增强适应不良过程,建议在这些系统稳定后开始高压氧疗程。

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