Benson N H, Maningas P A, Krohmer J R, Balcombe D J, Swor R
Ann Emerg Med. 1994 May;23(5):1047-8. doi: 10.1016/s0196-0644(94)70102-4.
Recognizing that prehospital thrombolytic therapy may provide benefit to certain subsets of patients, the routine prehospital use of thrombolytic agents should be discouraged pending further scientific delineation and documentation of those subgroups. ACEP encourages further investigation to document feasibility, efficacy, cost-effectiveness, and safety of use of these agents in this environment. Detailed education is needed in such areas as contraindications and the mechanics of drug administration. Online medical direction is paramount to the successful use of these agents in the prehospital setting.
认识到院前溶栓治疗可能对某些特定患者亚组有益，但在进一步科学界定和记录这些亚组之前，应不鼓励常规院前使用溶栓药物。美国急诊医师学会鼓励进一步开展研究，以记录这些药物在此环境下使用的可行性、有效性、成本效益和安全性。在诸如禁忌证和药物给药机制等领域需要进行详细培训。在线医疗指导对于在院前环境中成功使用这些药物至关重要。
