Goetz O
MMW Munch Med Wochenschr. 1976 Apr 23;118(17):541-4.
Virus infections during immunosuppression are like those with congenital defective immunity. Humoral and cellular immunity and interferon production are affected. In children the primary infection is prominent, in adults the reactivation. Cytomegaly, varicella, herpes and herpes simplex are given as examples of virus infections due to treatment. If the lymphocyte count falls below 500/ml, the virus infection threatens to become generalized. The possibilities of effective therapy are still very small at present. Warning is given against the use of cytosine arabinoside.
免疫抑制期间的病毒感染类似于先天性免疫缺陷时的感染。体液免疫、细胞免疫及干扰素生成均受影响。儿童以原发性感染为主,成人则以复发为主。巨细胞、水痘、疱疹及单纯疱疹被作为治疗所致病毒感染的例子。如果淋巴细胞计数降至500/ml以下,病毒感染有扩散的危险。目前有效治疗的可能性仍然很小。警告不要使用阿糖胞苷。