Kotoh T, Arima S, Futami K
Dept. of Surgery, Fukuoka University Chikushi Hospital.
Gan To Kagaku Ryoho. 1994 May;21(6):881-4.
A 64-year-old women with gallbladder cancer was treated by extended cholecystectomy and regional lymph node dissection. At 18 months after surgery, an enlarged retroperitoneal lymph node due to recurrence was demonstrated by computed tomography, and CEA and CA 19-9 showed high serum levels. Combination chemotherapy consisting of UFT administered orally at 200 mg daily and CDDP infused at 40 mg/m2 every 2 weeks was performed in 3 courses. After this therapy, the retroperitoneal lymph node was undetectable by computed tomography and both CEA and CA 19-9 decreased to within normal levels. It appeared that this chemotherapy is effective for gallbladder cancer.
一名64岁的胆囊癌女性患者接受了扩大胆囊切除术和区域淋巴结清扫术。术后18个月,计算机断层扫描显示因复发导致腹膜后淋巴结肿大,癌胚抗原(CEA)和糖类抗原19-9(CA 19-9)血清水平升高。进行了3个疗程的联合化疗,方案为口服优福定(UFT)每日200毫克,每2周静脉输注顺铂(CDDP)40毫克/平方米。该治疗后,计算机断层扫描未检测到腹膜后淋巴结,CEA和CA 19-9均降至正常水平。看来这种化疗对胆囊癌有效。