Miller S H, Rusenas I
Plast Reconstr Surg. 1976 May;57(5):627-36. doi: 10.1097/00006534-197605000-00011.
Human fingertip avulsion injuries were simulated by excising volar digital pads in stump-tailed monkeys. Half the defects were covered with split-skin grafts from the forearm, and half with full-thickness grafts of fingertip skin. Innervated pacinian corpuscles were found in the center of these grafts 3 months after the operation. The site of origin of these corpuscles is undefined. Denervation and devascularization of pacinian corpuscles resulted in alterations of their gross architecture, size, and innervation. The possibility exists that these alterations result from a dynamic adaptation of pacinian corpuscles to environmental stress.
通过切除短尾猴的手掌指垫来模拟人类指尖撕脱伤。一半的缺损用来自前臂的中厚皮片覆盖，另一半用指尖全厚皮片覆盖。术后3个月在这些移植皮片中发现了有神经支配的环层小体。这些小体的起源部位尚不清楚。环层小体的去神经支配和血运障碍导致其大体结构、大小和神经支配发生改变。这些改变有可能是环层小体对环境压力的动态适应所致。
